[Determination of phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum by high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry and preliminary study of the identification of adulteration].
Identifieur interne : 000629 ( Main/Exploration ); précédent : 000628; suivant : 000630[Determination of phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum by high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry and preliminary study of the identification of adulteration].
Auteurs : Lei Chen [République populaire de Chine] ; Yun Liu [République populaire de Chine] ; Lei Chen [République populaire de Chine] ; Xiaoyan Zhang [République populaire de Chine] ; Feng Feng [République populaire de Chine] ; Feng Zhang [République populaire de Chine]Source :
- Se pu = Chinese journal of chromatography [ 1000-8713 ] ; 2019.
Descripteurs français
- KwdFr :
- MESH :
- analyse : Gommes végétales, Phénols, Propolis.
- composition chimique : Populus.
- Chromatographie en phase liquide à haute performance, Contamination de médicament, Spectrométrie de masse.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Phenols, Plant Gums, Propolis.
- chemistry : Populus.
- Chromatography, High Pressure Liquid, Drug Contamination, Mass Spectrometry.
Abstract
High-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (HPLC/Q-TOF MS) was used to analyze 23 phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum. Propolis and poplar gum samples were dissolved in methanol-water (1:1, v/v) and filtered by 0.45 μm organic phase filtration membrane. The separation was carried out in an Agilent Eclipse Plus C18 column with gradient elution using acetoni-trile and 0.1% (volume percentage) formic acid solution as the mobile phases. The compounds were detected using positive ion electrospray ionization in full scan mode (m/z 100-1000). The quantification analysis was performed by the external standard method. The results showed that all the compounds were linear, with correlation coefficients>0.99, in the range of 10-20 μg/L. The limits of detection and limits of quantification for tangeretin and formononetin were 0.2 and 1 μg/L, respectively, and those for the other compounds were 2 and 10 μg/L, respectively. At the spiked levels of 10, 25, and 50 mg/kg, the recoveries of all the compounds ranged from 70.2% to 122.6%, with relative standard deviations of less than 10%. Salicin, cinnamic acid, caffeic acid, and coumaric acid could be used as markers for detecting adulteration in Chinese poplar propolis, while caffeic acid, ferulic acid, chrysin, caffeic acid phenethyl ester, pinocembrin, galangin, coumaric acid, isorhamnetin, kaempferide, and arte-pillin C could be used as markers for identifying Chinese poplar propolis and Brazil green propolis. The results presented in this paper may be helpful in quality control of propolis products.
DOI: 10.3724/SP.J.1123.2018.09003
PubMed: 30693708
Affiliations:
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Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Lei" sort="Chen, Lei" uniqKey="Chen L" first="Lei" last="Chen">Lei Chen</name><affiliation wicri:level="1"><nlm:affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xiaoyan" sort="Zhang, Xiaoyan" uniqKey="Zhang X" first="Xiaoyan" last="Zhang">Xiaoyan Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Feng" sort="Feng, Feng" uniqKey="Feng F" first="Feng" last="Feng">Feng Feng</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2019">2019</date><idno type="RBID">pubmed:30693708</idno><idno type="pmid">30693708</idno><idno type="doi">10.3724/SP.J.1123.2018.09003</idno><idno type="wicri:Area/Main/Corpus">000A56</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000A56</idno><idno type="wicri:Area/Main/Curation">000A56</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000A56</idno><idno type="wicri:Area/Main/Exploration">000A56</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Determination of phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum by high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry and preliminary study of the identification of adulteration].</title><author><name sortKey="Chen, Lei" sort="Chen, Lei" uniqKey="Chen L" first="Lei" last="Chen">Lei Chen</name><affiliation wicri:level="1"><nlm:affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Liu, Yun" sort="Liu, Yun" uniqKey="Liu Y" first="Yun" last="Liu">Yun Liu</name><affiliation wicri:level="1"><nlm:affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Lei" sort="Chen, Lei" uniqKey="Chen L" first="Lei" last="Chen">Lei Chen</name><affiliation wicri:level="1"><nlm:affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xiaoyan" sort="Zhang, Xiaoyan" uniqKey="Zhang X" first="Xiaoyan" last="Zhang">Xiaoyan Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019</wicri:regionArea><wicri:noRegion>Nanjing 210019</wicri:noRegion></affiliation></author><author><name sortKey="Feng, Feng" sort="Feng, Feng" uniqKey="Feng F" first="Feng" last="Feng">Feng Feng</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">Se pu = Chinese journal of chromatography</title><idno type="ISSN">1000-8713</idno><imprint><date when="2019" type="published">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Chromatography, High Pressure Liquid (MeSH)</term><term>Drug Contamination (MeSH)</term><term>Mass Spectrometry (MeSH)</term><term>Phenols (analysis)</term><term>Plant Gums (analysis)</term><term>Populus (chemistry)</term><term>Propolis (analysis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Chromatographie en phase liquide à haute performance (MeSH)</term><term>Contamination de médicament (MeSH)</term><term>Gommes végétales (analyse)</term><term>Phénols (analyse)</term><term>Populus (composition chimique)</term><term>Propolis (analyse)</term><term>Spectrométrie de masse (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Phenols</term><term>Plant Gums</term><term>Propolis</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Gommes végétales</term><term>Phénols</term><term>Propolis</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Populus</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Populus</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Chromatography, High Pressure Liquid</term><term>Drug Contamination</term><term>Mass Spectrometry</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Chromatographie en phase liquide à haute performance</term><term>Contamination de médicament</term><term>Spectrométrie de masse</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">High-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (HPLC/Q-TOF MS) was used to analyze 23 phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum. Propolis and poplar gum samples were dissolved in methanol-water (1:1, v/v) and filtered by 0.45 μm organic phase filtration membrane. The separation was carried out in an Agilent Eclipse Plus C18 column with gradient elution using acetoni-trile and 0.1% (volume percentage) formic acid solution as the mobile phases. The compounds were detected using positive ion electrospray ionization in full scan mode (<i>m/z</i> 100-1000). The quantification analysis was performed by the external standard method. The results showed that all the compounds were linear, with correlation coefficients>0.99, in the range of 10-20 μg/L. The limits of detection and limits of quantification for tangeretin and formononetin were 0.2 and 1 μg/L, respectively, and those for the other compounds were 2 and 10 μg/L, respectively. At the spiked levels of 10, 25, and 50 mg/kg, the recoveries of all the compounds ranged from 70.2% to 122.6%, with relative standard deviations of less than 10%. Salicin, cinnamic acid, caffeic acid, and coumaric acid could be used as markers for detecting adulteration in Chinese poplar propolis, while caffeic acid, ferulic acid, chrysin, caffeic acid phenethyl ester, pinocembrin, galangin, coumaric acid, isorhamnetin, kaempferide, and arte-pillin C could be used as markers for identifying Chinese poplar propolis and Brazil green propolis. The results presented in this paper may be helpful in quality control of propolis products.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">30693708</PMID><DateCompleted><Year>2019</Year><Month>02</Month><Day>12</Day></DateCompleted><DateRevised><Year>2019</Year><Month>02</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">1000-8713</ISSN><JournalIssue CitedMedium="Internet"><Volume>37</Volume><Issue>1</Issue><PubDate><Year>2019</Year><Month>Jan</Month><Day>08</Day></PubDate></JournalIssue><Title>Se pu = Chinese journal of chromatography</Title><ISOAbbreviation>Se Pu</ISOAbbreviation></Journal><ArticleTitle>[Determination of phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum by high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry and preliminary study of the identification of adulteration].</ArticleTitle><Pagination><MedlinePgn>40-45</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.3724/SP.J.1123.2018.09003</ELocationID><Abstract><AbstractText>High-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (HPLC/Q-TOF MS) was used to analyze 23 phenolic compounds in Chinese poplar propolis, Brazil green propolis, and poplar gum. Propolis and poplar gum samples were dissolved in methanol-water (1:1, v/v) and filtered by 0.45 μm organic phase filtration membrane. The separation was carried out in an Agilent Eclipse Plus C18 column with gradient elution using acetoni-trile and 0.1% (volume percentage) formic acid solution as the mobile phases. The compounds were detected using positive ion electrospray ionization in full scan mode (<i>m/z</i> 100-1000). The quantification analysis was performed by the external standard method. The results showed that all the compounds were linear, with correlation coefficients>0.99, in the range of 10-20 μg/L. The limits of detection and limits of quantification for tangeretin and formononetin were 0.2 and 1 μg/L, respectively, and those for the other compounds were 2 and 10 μg/L, respectively. At the spiked levels of 10, 25, and 50 mg/kg, the recoveries of all the compounds ranged from 70.2% to 122.6%, with relative standard deviations of less than 10%. Salicin, cinnamic acid, caffeic acid, and coumaric acid could be used as markers for detecting adulteration in Chinese poplar propolis, while caffeic acid, ferulic acid, chrysin, caffeic acid phenethyl ester, pinocembrin, galangin, coumaric acid, isorhamnetin, kaempferide, and arte-pillin C could be used as markers for identifying Chinese poplar propolis and Brazil green propolis. The results presented in this paper may be helpful in quality control of propolis products.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Yun</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xiaoyan</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>Animal, Plant and Food Inspection Center, Nanjing Customs, Nanjing 210019, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Feng</LastName><ForeName>Feng</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Feng</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Institute of Food Safety, Chinese Academy of Inspection and Quarantine, Beijing 100176, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>chi</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>China</Country><MedlineTA>Se Pu</MedlineTA><NlmUniqueID>9424804</NlmUniqueID><ISSNLinking>1000-8713</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010636">Phenols</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D053149">Plant Gums</NameOfSubstance></Chemical><Chemical><RegistryNumber>9009-62-5</RegistryNumber><NameOfSubstance UI="D011429">Propolis</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002851" MajorTopicYN="N">Chromatography, High Pressure Liquid</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004340" MajorTopicYN="Y">Drug Contamination</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013058" MajorTopicYN="N">Mass Spectrometry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010636" MajorTopicYN="N">Phenols</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053149" MajorTopicYN="N">Plant Gums</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011429" MajorTopicYN="N">Propolis</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">adulteration identification</Keyword><Keyword MajorTopicYN="N">high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (HPLC/Q-TOF MS)</Keyword><Keyword MajorTopicYN="N">phenolic compounds</Keyword><Keyword MajorTopicYN="N">propolis</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>1</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>1</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">30693708</ArticleId><ArticleId IdType="doi">10.3724/SP.J.1123.2018.09003</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chen, Lei" sort="Chen, Lei" uniqKey="Chen L" first="Lei" last="Chen">Lei Chen</name></noRegion><name sortKey="Chen, Lei" sort="Chen, Lei" uniqKey="Chen L" first="Lei" last="Chen">Lei Chen</name><name sortKey="Feng, Feng" sort="Feng, Feng" uniqKey="Feng F" first="Feng" last="Feng">Feng Feng</name><name sortKey="Liu, Yun" sort="Liu, Yun" uniqKey="Liu Y" first="Yun" last="Liu">Yun Liu</name><name sortKey="Zhang, Feng" sort="Zhang, Feng" uniqKey="Zhang F" first="Feng" last="Zhang">Feng Zhang</name><name sortKey="Zhang, Xiaoyan" sort="Zhang, Xiaoyan" uniqKey="Zhang X" first="Xiaoyan" last="Zhang">Xiaoyan Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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